MRI-Compatible, Easy Setup, Real-Time Feedback
Our Celeritas fMRI Response System accurately collects participant responses, gives the researcher real-time feedback of responses, and accepts the trigger pulse from the scanner. Simple setup with only one interface. Connect two response units at a time. Quickly interchangeable for different studies. 5-, 3-, and 2-button response units, as well as a joystick and foot pedals, are available.
The Celeritas button response units all work with the same control console and can be quickly changed to meet each study’s needs. The button units are custom molded to fit the ergonomics of a person laying down in the scanner to ensure they are able to comfortably respond during long scan sessions. All button units have included wrist straps to prevent the response units from being dropped in the scanner. The button units comfortably fit small to large hand sizes and are constructed entirely of non-metallic components – completely eliminating all metal inside the magnet room.
USB versions of our response units are perfect for practicing a task, perhaps in an MRI Simulator, prior to performing the task in the scanner. Celeritas USB response units are available for all BRU models. The USB units connect directly to the PC running the experiment and appear as a keyboard device.
The Celeritas Console includes both BNC and Optical connections to allow for conversion of the trigger pulse provided by the scanner into a keyboard button press. This feature allows for the synchronization of the scanner with the stimulus presentation software (E-Prime/MATLAB/etc.). The Celeritas system is able to provide millisecond-accurate responses when working with E-Prime.
The BRUs and Joysticks are assembled using chemical resistant, medical grade, biocompatible plastic. The chemical resistance allows for repeated cleaning without degradation of the material or color. The BRUs include a tactile indicator to ensure correct finger placement during experiments. The wrist sleds are adjustable for a more comfortable fit.
The Celeritas Fiber Optic Response System can be customized with the following components:
- Interface Console
- Celeritas Monitor Software
- Fiber Optic Button Response Units – two, three, or five-button (includes 4-meter cable)
- USB Response Units – two, three, or five-button (includes USB cable to connect to computer)
- Joysticks with omnidirectional analog stick and four buttons (include 4-meters of cable)
- 10, 20, or 30 meter fiber cables
Celeritas Console and Response Units
This product is intended for research use only.
Features
Celeritas BRU Features:
- Ergonomic design
- Wrist strap and adjustable wrist sled for a more comfortable fit
- Tactile indicator on index finger button to remind the participant of correct finger placement
- Molded from high-impact, chemical resistant, medical grade, biocompatible plastic
- Contains no metal or conductive materials
- Custom molded wall mount holder for BRUs,, joystick, and cabling (optional accessory)
Celeritas Joystick Features:
- Omnidirectional analog stick with four buttons
- Comfortable ambidextrous design
- Hand strap for comfortable positioning
- Molded from chemical resistant, medical grade, biocompatible plastic
- Contains no metal or conductive materials
- Custom molded wall mount holder for Joysticks and cabling (optional accessory)
Celeritas Fiber Optical Response System Features:
- Thin, flexible cabling with easy-to-attach connectors
- 10, 20, or 30 meter cabling
- Electrical and optical scanner trigger connections
- Supports any combination of BRUs, Joystick, and Foot Pedal
- Displays responses on the front panel in real-time
- Console permits responses in control room
- External digital inputs and outputs for interfacing with third-party equipment
- Connects as a standard USB keyboard and joystick (HID – Human Interface Device) when not using E-Prime
- Ability to mask scanner trigger key responses when device is not in use
- Can store ten custom key mapping profiles
- Optimized for increased performance when used with E-Prime®
Celeritas Monitor Features:
- User friendly interface for customization of BRU and trigger key mappings
- Ability to create and store unlimited custom key mapping configurations to user-created profiles
- Provides complete device status, feedback, and configuration information in a single, easy-to-understand window
- Ability to hide scanner trigger responses when the device is not in use
Enhanced Features with E-Prime:
- Ability to interact with the E-Prime 3.0 Button Device
- Ability to customize responses and key mappings with the joystick
- Automatically synchronizes with E-Prime’s clock for improved response time accuracy
- Ensures every response gets queued for increased reliability
- Deterministic time-stamping of responses
- Enhanced error checking of the Response Device status at run time
- Remapping of Joystick Keys
- Creation of Joystick zones
- Portability of custom key mappings to any Celeritas Device (key mapping stored in es2/es3 file)
Requirements
Hardware Requirements:
- Full speed USB port
- Optical or BNC Trigger input
Minimum Recommended Waveguide Diameter:
- Single Response Unit – 19.05 mm (.75″)
- Dual Response Units – 29.21 mm (1.15″)
Celeritas Mode Software Requirements:
- E-Prime 3.0/Windows 10, and 11
- E-Prime 2.0 SP2/Windows 10
NOTE: HID mode does not require E-Prime software. The Celeritas System will connect as a standard USB keyboard device.
Selected Pub Med Central Publications
A subset of research publications using our Celeritas Response System in MRI and MEG:
Ophey A, Röttgen S, Pauquet J, Weiß KL, Scharfenberg D, Doppler CEJ, Seger A, Hansen C, Fink GR, Sommerauer M, Kalbe E. Cognitive training and promoting a healthy lifestyle for individuals with isolated REM sleep behavior disorder: study protocol of the delayed-start randomized controlled trial CogTrAiL-RBD. Trials. 2024 Jun 28;25(1):428. doi: 10.1186/s13063-024-08265-9. PMID: 38943191; PMCID: PMC11214208. (Pub Med Central)
Krebs C, Brill E, Minkova L, Federspiel A, Kellner-Weldon F, Wyss P, Teunissen CE, van Harten AC, Seydell-Greenwald A, Klink K, Züst MA, Brem AK, Klöppel S. Investigating Compensatory Brain Activity in Older Adults with Subjective Cognitive Decline. J Alzheimers Dis. 2023;93(1):107-124. doi: 10.3233/JAD-221001. PMID: 36970895; PMCID: PMC10200167. (Pub Med Central)
Tisdall L, Mata R. Age differences in the neural basis of decision-making under uncertainty. Cogn Affect Behav Neurosci. 2023 Jun;23(3):788-808. doi: 10.3758/s13415-022-01060-6. Epub 2023 Mar 8. PMID: 36890341; PMCID: PMC10390623. (Pub Med Central)
Tisdall L, Mugume S, Kellen D, Mata R. Lifespan trajectories of risk preference, impulsivity, and self-control: A dataset containing self-report, informant-report, behavioral, hormone and functional neuroimaging measures from a cross-sectional human sample. Data Brief. 2023 Dec 15;52:109968. doi: 10.1016/j.dib.2023.109968. PMID: 38152498; PMCID: PMC10751829. (Pub Med Central)
Paas Oliveros LK, Cieslik EC, Pieczykolan A, Pläschke RN, Eickhoff SB, Langner R. Brain functional characterization of response-code conflict in dual-tasking and its modulation by age. Cereb Cortex. 2023 Sep 9;33(18):10155-10180. doi: 10.1093/cercor/bhad273. PMID: 37540164; PMCID: PMC10502578. (Pub Med Central)
Fernandino L, Tong JQ, Conant LL, Humphries CJ, Binder JR. Decoding the information structure underlying the neural representation of concepts. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2108091119. doi: 10.1073/pnas.2108091119. PMID: 35115397; PMCID: PMC8832989. (Pub Med Central)
Ludyga S, Hanke M, Leuenberger R, Bruggisser F, Pühse U, Gerber M, Lemola S, Capone-Mori A, Keutler C, Brotzmann M, Weber P. Martial Arts and Cognitive Control in Children with Attention-Deficit Hyperactivity Disorder and Children Born Very Preterm: A Combined Analysis of Two Randomized Controlled Trials. Med Sci Sports Exerc. 2023 May 1;55(5):777-786. doi: 10.1249/MSS.0000000000003110. Epub 2022 Dec 28. PMID: 36728805; PMCID: PMC10090288. (Pub Med Central)
Simmonite M, Polk TA. Age-related declines in neural distinctiveness correlate across brain areas and result from both decreased reliability and increased confusability. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2022 May;29(3):483-499. doi: 10.1080/13825585.2021.1999383. Epub 2021 Nov 10. PMID: 34757860; PMCID: PMC8960331. (Pub Med Central)
Tong J, Binder JR, Humphries C, Mazurchuk S, Conant LL, Fernandino L. A Distributed Network for Multimodal Experiential Representation of Concepts. J Neurosci. 2022 Sep 14;42(37):7121-7130. doi: 10.1523/JNEUROSCI.1243-21.2022. Epub 2022 Aug 8. PMID: 35940877; PMCID: PMC9480893. (Pub Med Central)
Maldonado Moscoso PA, Greenlee MW, Anobile G, Arrighi R, Burr DC, Castaldi E. Groupitizing modifies neural coding of numerosity. Hum Brain Mapp. 2022 Feb 15;43(3):915-928. doi: 10.1002/hbm.25694. Epub 2021 Dec 8. PMID: 34877718; PMCID: PMC8764479. (Pub Med Central)
Guterstam A, Bio BJ, Wilterson AI, Graziano M. Temporo-parietal cortex involved in modeling one’s own and others’ attention. Elife. 2021 Feb 15;10:e63551. doi: 10.7554/eLife.63551. PMID: 33587038; PMCID: PMC7884070. (Pub Med Central)
Cohen AD, Bruña R, Chang YF, Cheng Y, Doman J, Huppert T, Kim T, Maestu F, Roush RE, Snitz BE, Becker JT. Connectomics in Brain Aging and Dementia – The Background and Design of a Study of a Connectome Related to Human Disease. Front Aging Neurosci. 2021 Oct 7;13:669490. doi: 10.3389/fnagi.2021.669490. PMID: 34690734; PMCID: PMC8530182. (Pub Med Central) * MRI and MEG
Reinhardt J, Rus-Oswald OG, Bürki CN, Bridenbaugh SA, Krumm S, Michels L, Stippich C, Kressig RW, Blatow M. Neural Correlates of Stepping in Healthy Elderly: Parietal and Prefrontal Cortex Activation Reflects Cognitive-Motor Interference Effects. Front Hum Neurosci. 2020 Sep 29;14:566735. doi: 10.3389/fnhum.2020.566735. PMID: 33132879; PMCID: PMC7550687. (Pub Med Central)
Cassady K, Gagnon H, Freiburger E, Lalwani P, Simmonite M, Park DC, Peltier SJ, Taylor SF, Weissman DH, Seidler RD, Polk TA. Network segregation varies with neural distinctiveness in sensorimotor cortex. Neuroimage. 2020 May 15;212:116663. doi: 10.1016/j.neuroimage.2020.116663. Epub 2020 Feb 25. PMID: 32109601; PMCID: PMC7723993. (Pub Med Central)
Guterstam A, Wilterson AI, Wachtell D, Graziano MSA. Other people’s gaze encoded as implied motion in the human brain. Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):13162-13167. doi: 10.1073/pnas.2003110117. Epub 2020 May 26. PMID: 32457153; PMCID: PMC7293620. (Pub Med Central)
Ethofer T, Stegmaier S, Koch K, Reinl M, Kreifelts B, Schwarz L, Erb M, Scheffler K, Wildgruber D. Are you laughing at me? Neural correlates of social intent attribution to auditory and visual laughter. Hum Brain Mapp. 2020 Feb 1;41(2):353-361. doi: 10.1002/hbm.24806. Epub 2019 Oct 22. PMID: 31642167; PMCID: PMC7268062. (Pub Med Central)
Gagnon H, Simmonite M, Cassady K, Chamberlain J, Freiburger E, Lalwani P, Kelley S, Foerster B, Park DC, Petrou M, Seidler RD, Taylor SF, Weissman DH, Polk TA. Michigan Neural Distinctiveness (MiND) study protocol: investigating the scope, causes, and consequences of age-related neural dedifferentiation. BMC Neurol. 2019 Apr 12;19(1):61. doi: 10.1186/s12883-019-1294-6. PMID: 30979359; PMCID: PMC6460537. (Pub Med Central)
Raghuraman N, Wang Y, Schenk LA, Furman AJ, Tricou C, Seminowicz DA, Colloca L. Neural and behavioral changes driven by observationally-induced hypoalgesia. Sci Rep. 2019 Dec 24;9(1):19760. doi: 10.1038/s41598-019-56188-2. PMID: 31874985; PMCID: PMC6930247. (Pub Med Central) * MEG
Berman BD, Groth CL, Shelton E, Sillau SH, Sutton B, Legget KT, Tregellas JR. Hemodynamic responses are abnormal in isolated cervical dystonia. J Neurosci Res. 2020 Apr;98(4):692-703. doi: 10.1002/jnr.24547. Epub 2019 Nov 6. PMID: 31692015; PMCID: PMC7015799. (Pub Med Central)
Koch K, Stegmaier S, Schwarz L, Erb M, Thomas M, Scheffler K, Wildgruber D, Nieratschker V, Ethofer T. CACNA1C risk variant affects microstructural connectivity of the amygdala. Neuroimage Clin. 2019;22:101774. doi: 10.1016/j.nicl.2019.101774. Epub 2019 Mar 12. PMID: 30909026; PMCID: PMC6434179. (Pub Med Central)
Schenk LA, Colloca L. The neural processes of acquiring placebo effects through observation. Neuroimage. 2020 Apr 1;209:116510. doi: 10.1016/j.neuroimage.2019.116510. Epub 2019 Dec 30. PMID: 31899287; PMCID: PMC7107761. (Pub Med Central)
Gao C, Conte S, Richards JE, Xie W, Hanayik T. The neural sources of N170: Understanding timing of activation in face-selective areas. Psychophysiology. 2019 Jun;56(6):e13336. doi: 10.1111/psyp.13336. Epub 2019 Feb 2. PMID: 30710345; PMCID: PMC6508977. (Pub Med Central)
Colloca L, Schenk LA, Nathan DE, Robinson OJ, Grillon C. When Expectancies Are Violated: A Functional Magnetic Resonance Imaging Study. Clin Pharmacol Ther. 2019 Dec;106(6):1246-1252. doi: 10.1002/cpt.1587. Epub 2019 Sep 10. PMID: 31350784; PMCID: PMC6851406. (Pub Med Central)
Kubica J, Szymura J, Domagalik A, Golda S, Wiecek M, Fafrowicz M, Marek T, Pera J. Systematic Balance Exercises Influence Cortical Activation and Serum BDNF Levels in Older Adults. J Clin Med. 2019 Nov 7;8(11):1910. doi: 10.3390/jcm8111910. PMID: 31703409; PMCID: PMC6912622. (Pub Med Central)
Gawlowska M, Domagalik A, Beldzik E, Marek T, Mojsa-Kaja J. Dynamics of error-related activity in deterministic learning – an EEG and fMRI study. Sci Rep. 2018 Oct 2;8(1):14617. doi: 10.1038/s41598-018-32995-x. PMID: 30279558; PMCID: PMC6168565. (Pub Med Central)
Koch K, Stegmaier S, Schwarz L, Erb M, Reinl M, Scheffler K, Wildgruber D, Ethofer T. Neural correlates of processing emotional prosody in unipolar depression. Hum Brain Mapp. 2018 Aug;39(8):3419-3427. doi: 10.1002/hbm.24185. Epub 2018 Apr 22. PMID: 29682814; PMCID: PMC6866387. (Pub Med Central)
Mohl B, Berman BD, Shelton E, Tanabe J. Levodopa response differs in Parkinson’s motor subtypes: A task-based effective connectivity study. J Comp Neurol. 2017 Jun 15;525(9):2192-2201. doi: 10.1002/cne.24197. Epub 2017 Mar 23. PMID: 28256710; PMCID: PMC6301039. (Pub Med Central)
Fuertinger S, Horwitz B, Simonyan K. The Functional Connectome of Speech Control. PLoS Biol. 2015 Jul 23;13(7):e1002209. doi: 10.1371/journal.pbio.1002209. PMID: 26204475; PMCID: PMC4512708. (Pub Med Central)
Simonyan K, Berman BD, Herscovitch P, Hallett M. Abnormal striatal dopaminergic neurotransmission during rest and task production in spasmodic dysphonia. J Neurosci. 2013 Sep 11;33(37):14705-14. doi: 10.1523/JNEUROSCI.0407-13.2013. PMID: 24027271; PMCID: PMC3771037. (Pub Med Central)
